Polynucleotides: Your Skin's cellular comeback
- Michelle Adams
- Sep 29
- 2 min read
In the ever-evolving world of aesthetics, Polynucleotides are taking centre stage. Once reserved for wound healing, these DNA molecules are stepping into the spotlight, not as a trend but as a transformative tool for skin regeneration.
So what exactly are Polynucleotides and why are they becoming a must-have for practitioners and patients?
What are Polynucleotides?
Polynucleotides are highly purified DNA fragments, typically extracted from trout. Whilst that might sound niche, their function is anything but: these molecules mimic the building blocks already found in our cells. When introduced into aged or damaged skin, they act like cellular coaches - stimulating fibroblasts - the cells responsible for connective tissue formation. This kick starts the skins natural healing process.
In short, we're not just treating the surface, we are healing the skin from within.
How do they work?
Polynucleotides are delivered by injectable gels. They get to work by:
Stimulating fibroblasts to encourage cell turnover
Boosting collagen production and elasticity
Deeply hydrating the skin through powerful wound-healing polymers
Calming inflammation and rebalancing melanocyte activity for a more even skin tone.
This multi-tasking magic makes them ideal for a wide range of concerns.
Where can they be used?
Face: fine lines, dark under-eye circles, acne scarring
Neck and decolletage
Scalp
Body: inner arms, thighs, hands.
Polynucleotides can be used alone as a stand alone treatment or in combination with other treatments like fillers, microneedling and anti wrinkle treatment.
What can you expect?
Initial results typically appear around the three week mark, with improvements continuing over six-nine months. A course of three sessions is advised, 3 weeks apart, with a maintenance session at 6 months. Side effects are minimal, usually limited to slight redness around the injection site.
Why do we love them?
At the heart of polynucleotide therapy is a philosophy that aligns with our clinic: regeneration over correction, cellular health over surface fixes. Polynucleotides empower the skin to restore itself...and we love that!
If you are curious about what this amazing treatment can do for you, you can CLICK HERE for a free consultation and we can dive deeper into how you can achieve the results you've been looking for.
Look forward to seeing you in clinic
Michelle



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